Possible, yes.Avis, among several others, will offer it. BUT THE COST IS AROUND 20 TH. ROUBLES ($700) JUST FOR THIS SERVICE ALONE, ON TOP OF THE DAILY RENTAL (AT THE VERY LEAST $150/DAY). Financially it will cost you about the same as to hire a driver with a car. See my www.moscowdrivers.net list. $1500 will cover a two-way trip regardless of time it takes.
If you know of a company that offers one-way rental without charging an outrageous amount please let me know. I know that special deal come up in the summer but does anybody offer one-way car rental at a reasonable rate? The total cost for one way economy car should be no more than $600-700.